Injectable diabetes medications have gained popularity in recent years due to their effectiveness in managing diabetes. Since they are also effective at promoting weight loss, they are being prescribed as a weight loss medication.

In this article, we will explore three commonly used medications in this category: Ozempic, Mounjaro, and Wegovy. Although each medication has its unique characteristics, they all belong to a class known as GLP-1 receptor antagonists. We will cover medication mechanisms, benefits, and the significance of lifestyle changes when utilizing these medications.

How do these medications work?

These new injectable medications like Ozempic, Mounjaro, and Wegovy belong to the class of GLP-1 receptor antagonists. These medications mimic the action of GLP-1, a hormone that regulates blood sugar and appetite.

By enhancing insulin release and reducing glucagon production (glucagon is the production of glucose made in the liver), they lower blood sugar levels and improve glycemic control in diabetes patients. Additionally, they slow down stomach emptying and create a sense of fullness and reducing appetite. This aids in weight loss by decreasing calorie intake over time.

Pros of taking medication:

  1. Decreased mental chatter involving food choices: My patients are saying, “it helps to decrease or eliminate the mental chatter that involves food choices.” This mental chatter often includes cravings, urges, and thoughts about food, which can be challenging to resist. By suppressing appetite and regulating satiety hormones, these medications help you gain control over your eating habits and reduce the preoccupation with food.
  2. Effective weight loss: All three medications have been shown to be effective in promoting weight loss, making them valuable options if you are struggling with obesity.
  3. Potential cardiovascular benefits: Certain GLP-1 receptor antagonists provide cardiovascular benefits beyond blood sugar control. Research indicates reduced risks of heart attacks and strokes in type 2 diabetes patients with existing cardiovascular disease.
  4. Convenience and ease of use: Injectable diabetes/weight loss meds are usually taken weekly or daily, depending on the type. This dosing convenience simplifies treatment. Unlike other interventions or meds needing multiple daily doses, injectables offer simplicity, aiding medication adherence.


  1. Dependency on medication: Dependency on medication can develop if you rely solely on it for weight loss, neglecting the need for necessary lifestyle changes. Once you stop taking the medication, you are likely to fall back into old habits and regain the weight you lost.
  2. Side effects: These drugs can cause common side effects like nausea, vomiting, diarrhea, abdominal pain, injection site reactions, and skin hyperpigmentation. Although side effects often decrease over time they can still be bothersome, even debilitating for some people.
  3. Sustainable weight management: Sustainable weight management necessitates long-term lifestyle changes, including a healthy diet and regular physical activity. Weight loss medications can initiate the process, but without sustainable changes, their effects may only be temporary.
  4. Cost: These medications can be expensive, especially without insurance coverage. The high cost may make them inaccessible or unaffordable for many people.
  5. Health risks: Depending solely on medication without addressing lifestyle factors may lead to potential health risks. Obesity is often associated with other health conditions such as cardiovascular diseases, high blood pressure, and diabetes. Lifestyle changes, including a balanced diet and regular exercise, can help manage these conditions and improve overall health.

It’s important to note that the experiences and opinions of patients may vary, and individual results may differ. Consulting with a healthcare professional is crucial to determine the appropriateness of these medications for specific individuals and to ensure they are used as part of a comprehensive treatment plan.


Injectable diabetes and weight loss medications like Ozempic, Mounjaro, and Wegovy mimic GLP-1 effects, regulating blood sugar, reducing appetite, and aiding weight loss. However, it is crucial to understand that medication alone is insufficient.

To achieve lasting success, it is necessary to combine medication with lifestyle modifications, such as a healthy diet and regular exercise. This combination offers individuals the greatest opportunity for sustainable weight loss and enhanced management of diabetes. It is always advisable to seek personalized advice and guidance from a healthcare professional regarding these medications.